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GST inhibitors GST inhibitors reverse tumor resistance by means of suppressing GST activity and improving the chemotherapeutic drug sensitivity of tumor cells

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To exclude the possibility of transgenic expression artifacts, we monitored mutant phenotypes of animals bearing metastable protein alleles in RAS, let-60(ga89), and paramyosin, unc-15(e1401 ), which are highly sensitive to changes in the protein folding environment