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The honest caveat is that this specific pairing has not been run through a published human combination trial, so the combined number remains a reasoned projection rather than a trial result

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In fact, age-related loss of hippocampal function can be restored by transplantation of NRF2-overexpressing young but not old NSCs, indicating that NRF2 is a critical mediator of NSC/NPC-dependent neurogenesis with age (Ray et al., 2018)