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Both drugs are GLP-1 receptor agonists that curb appetite and regulate blood sugar, especially when paired with healthy habits

This multi-receptor mechanism distinguishes it from earlier weight-management medicines such as semaglutide (Wegovy) or tirzepatide (Mounjaro), and it also explains why gastrointestinal effects including changes to bowel habits are among the most frequently reported experiences in clinical trials

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The rationale: methionine is consumed rapidly during active fat oxidation, and twice-weekly administration prevents the mid-week concentration dip that can slow lipolysis