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Because tirzepatide acts at both GLP-1 and GIP receptors, the article describes simultaneous shifts in blood glucose, blood pressure, and neurotransmitter release, which it links to tension-type or migraine-like head pain

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Age-related changes in cerebrovascular reactivity and their relationship to cognition: a four-year longitudinal study

Thus, individuals with impaired glucose tolerance or diabetes mellitus have reduced NK cell activity, which might help to explain why patients with diabetes mellitus are more susceptible to COVID-19 and have a worse prognosis than those without diabetes mellitus