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Semaglutide produced about 15% average body-weight loss in the STEP trials over 68 weeks (Wilding et al., N Engl J Med, 2021)
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People who expect smooth, linear progress are frequently frustrated during these transition periods and may make unnecessary changes to their diet or exercise in response to perceived stalls
5 Lurasidone is theorized to cause nausea due to partialrather than fullagonism of 5-HT 1a receptors with decreased D 2 receptor antagonism at doses lower than 160 mg daily
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