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One possible explanation is that EMT-induced changes in cancer cell secretory proteins establish autocrine signaling loops involving key pathways like TGF- and Wnt--catenin, which are crucial for maintaining stem cell characteristics [80]

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demonstrated greater survival, preserved LV function, decreased myocyte apoptosis and reduced caspase-3 activation on chronic GLP-1 infusion in spontaneously hypertensive, heart failure prone rats [74]

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