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Such a strategy could include thyroid function assessment at GLP-1RA initiation, and every 3 months during active weight loss period (or more frequent, e.g., every month when 5% weight reduction is achieved), and timely levothyroxine dose titration to optimize thyroid hormone replacement
Kistorp, C., Bliddal, H., Goetze, J
For understanding the stack this means: the order and the joint presence of both signals is mechanistically relevant, not just the sum of two individual doses
Julio Rosenstock, the trials lead investigator and a clinical professor at UT Southwestern, summarized it plainly: These complete 26-week COURAGE results demonstrate a meaningful opportunity to preserve muscle mass while enhancing fat loss. 1 The Safety Problem Nobody Wants to Talk About The efficacy data is impressive
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