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"All of those things have made me feel more like getting up and exercising," he said, "Ive been doing more cardio, walking several times a week, and also adding in some strength training exercises as well." "Exercise releases endorphins and dopamine to the brain," Mark explained, "It gives you a sense of confidence and relaxation, as well as energy to move about and socialize more

and (4) metformin is safe, well-tolerated and cost-effective, making it an attractive addition to a cytotoxic therapeutic regimen, and it can be administered orally alongside infusional 5FU

Framing it this way keeps the treatment grounded in sound medicine rather than overstated promises

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