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Due to its plasma half-life of approximately 3.8-6.9 hours, a twice-daily (BID) dosing schedule may be used to provide more consistent and sustained inhibition of NNMT throughout the day, potentially maximizing its metabolic effects
Always consult your healthcare provider before starting any new supplement.
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
Phase Weeks 3+ (standard) Daily dose 100 mg once daily Notes The most common research community target dose
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