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Constipation is a recognized gastrointestinal side effect in major GLP-1 weight-loss trials, especially during dose escalation or when reduced appetite leads people to eat and drink less

[10] Weight loss from Ozempic may eventually improve OSA symptoms, but any sleep disturbances should be evaluated by a healthcare professional

The FDA is not going to accept it works in obese patients as sufficient grounds for a broad AUD label without a corresponding mechanistic story that holds at the receptor level across diverse populations

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