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Therefore, cortical GABA has a beneficial rather than a detrimental role in PD, and GABA reduction may donate to increased motor symptom expression (van Nuland et al

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For example, cancer-associated fibroblasts (CAFs) can supply metabolic substrates to tumors through the reverse Warburg effect, while regulatory T cells and tumor-associated macrophages (TAMs) assist tumors in evading immune surveillance and promoting invasion and metastasis by competitively consuming nutrients such as glucose and amino acids or secreting immunosuppressive metabolites (e.g., lactate) [319]

Daousi, C., Pinkney, J