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The modern GLP-1RA class evolved following identification of exendin-4, a GLP-1 analogue originally isolated from Gila monster venom [22]

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Kim J, Park M, Jeong W, Lee HW, Lee G, Lee KS, Park SW, Choi J

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Because this study was done with patients with type 2 diabetes, its worth pointing out that it looked at Ozempic and Mounjaro rather than Wegovy and Zepbound, respectively, as NBC News and Forbes have incorrectly reported

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CJC-1295 stimulates pituitary GH release via the GHRH receptor while ipamorelin stimulates the same cells via the GHS-R1a (ghrelin) receptor

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