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The level of GSH/GSSG in the cells treated with NS for more than 6 h was also significantly decreased, but the extent was smaller than that in the NSBSO group, indicating that the combination of consumption of existing GSH and inhibition of GSH synthesis promotes the exhaustion of GSH in cells
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In addition to the endogenous cellular pathways, recent studies have also investigated the role of the gut microbiome in affecting NAD + levels
To increase its bioactivity and bioavailability resveratrol is encapsulated inside liposomes which acts as an ideal solution for its activity as resveratrol is less soluble in water
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