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Les sulfamides hypoglycmiants (glibenclamide, gliclazide, glimpiride) baissent l'HbA1c d'environ 0,7 1,2 %, mais avec deux inconvnients majeurs : ils font prendre du poids (+1 +3 kg en moyenne) et prsentent un risque rel d'hypoglycmie
Weight-loss medications in the 20th century proved to be equally dangerous: dinitrophenol, a mitochondrial proton pump uncoupler, was remarkably effective at shedding pounds but led to nerve malfunction and arrhythmia induced fatalities
You need to get it from food or supplements
Together, they may provide synergistic effects
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