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When it fails, the consequences can be severe
The NHS side-effects guidance for hydroxocobalamin, the form used in the UK, lists nausea, headache, dizziness and injection-site reactions as known effects that usually pass on their own
B12 is derived from foods of animal origin such as meat, liver, fish, and eggs
Animal-model evidence consistently shows local effects: angiogenesis at the injury site (VEGF upregulation), growth-factor signaling (EGF, FGF), nitric oxide pathway modulation, and accelerated tendon-to-bone interface healing in rat Achilles transection studies
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