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B12 is water-soluble and any excess is excreted in urine there is no established upper tolerable intake level for B12 and toxicity from injection at standard doses has not been reported
However, experts in the area generally concur that a combination of data from multiple endpoints is needed to discriminate sensitizing and/or irritant substances in vitro
An empty stomach combined with any subcutaneous injection can produce temporary queasiness in some individuals
The result is more consistent IGF-1 elevation, more pronounced body composition changes at the 3-month mark, and better long-term anti-aging outcomes
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