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Providers should weigh the health benefits of better glycemic control and weight reduction against the patients ability to tolerate higher dosages

Folate deficiency caused by a lack of dietary folate is more common in people who have a generally unbalanced and unhealthy diet, people who regularly misuse alcohol and people following a fad diet that doesnt involve eating good sources of folate

The gradual dose escalation protocol specifically aims to minimize these effects while building therapeutic benefit

Song Y, Li J, Tian H et al (2023) Copper chelating peptides derived from tilapia ( Oreochromis niloticus ) skin as tyrosinase inhibitor: biological evaluation, in silico investigation and in vivo effects