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Circulating levels decline with age, from roughly 200 ng/mL at age 20 to about 80 ng/mL by 60. Small split-face human dermatology studies, usually with fewer than 50 participants per arm, report changes in wrinkle depth and skin density
Also, those who have anemia or are vegetarian or vegan will want to consider a B12 regimen, as vegetable-based diets generally dont contain the amount of B12 that you need to thrive
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