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Some clinical trials of GLP-1 agonists have included participants taking various antidepressants, though specific safety data for this combination is limited
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Nrf2/Keap1/ARE Redox Regulatory Pathway In response to oxidative or xenobiotic stress, Nrf2 dissociates from its inhibitor Keap1, translocates to the nucleus, and binds antioxidant response elements (ARE) to induce expression of genes involved in antioxidant defense and GSH biosynthesis (41)
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