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It's not just about health problems
The same audience that adopted rapamycin and metformin off-label is already running the unsupervised version of this experiment with semaglutide and tirzepatide, frequently sourced from the gray market, frequently without the laboratory monitoring and clinical oversight that on-label use receives
Medicare and Medicaid may also offer coverage under specific conditions
Patients using tirzepatide continuously maintained approximately 8590% of weight loss at two-year follow-up
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