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Indications: Huntington's Chorea (a hyperkinetic movement disorder) A drug of first choice for this condition Side Effects: Sedation Depression (suicidal tendencies) Parkinsonism symptoms Lacks the hypotensive & GI side effects of reserpine due to its selectivity for central VMAT2 Pharmacokinetics: * undergoes rapid hepatic metabolism involving carbonyl reductase and CYP2D6 to 2 active metabolites -dihydrotetrabenazine (-HTBZ) and -dihydrotetrabenazine (-HTBZ), with eventual renal elimination of metabolites the -HTBZ and -HTBZ metabolites are primarily responsible for the pharmacological & therapeutic effects produced by the parent prodrug Readily crosses the blood brain barrier & depletes cerebral monoamine stores
Increasing glutathione and its supporting enzymes has been shown to reduce oxidative damage and help remove toxic substances from the body
Cukup konsumsi satu kali satu kaplet Fitergy setiap harinya
Fatigue and Dizziness: With hormone-related fatigue can be common during menopause, a reduction in calories and potential dehydration associated with GLP-1 usage can compound these symptoms (8)
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