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Acknowledgements The authors would like to thank the participants of the study and the study personnel

Tendons require mechanical stimulus to guide proper collagen organization

The first comes from the blood, where DNA methylation clocks such as Systems Age from TruDiagnostics, Proteomics-based aging clocks like those from Vero, and RNA signatures read the activity of brain specific aging-associated genes, which is the basis of the NeuroAge panel

Intracellular ROS homeostasis ROS are a class of oxygen-containing and highly reactive substances, generated within cells from both endogenous and exogenous sources [36]