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Approved in November 2023, Zepbound represents a dual agonist approach to metabolic regulation, targeting both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors
doi: 10.1038/s41598-017-17718-y 245 WatsonKTWroolieTETongGFoland-RossLCFrangouSSinghMet al
Monthly dose adjustments proceed systematically through 0.5 mg, 1.0 mg, 1.7 mg, and potentially 2.4 mg based on individual response patterns
A prospective case series study found that GLP-1RAs, such as liraglutide and exenatide, reduced the population of cutaneous T cells and the expression of IL-17 in skin lesions
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