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Normal erythrocytes are protected from high-dose ascorbate due to their increased level of antioxidant enzymes like GSH and have an enhanced glucose flux into the pentose phosphate (PP) pathway to generate more NADPH, which is a crucial molecule for the recovery of GSH
Pizzino G, Irrera N, Cucinotta M, Pallio G, Mannino F, Arcoraci V, Squadrito F, Altavilla D, Bitto A
These selenoenzymes take part either in the antioxidant protection of cells, in the modification of the redox status and the thyroid hormone metabolism [19]
These impacts included improved cardiovascular benefits, less joint pain, lower cholesterol and blood pressure, improved mood and energy levels and more
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