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Together these adversities might result in variable results or poor compliance hampering the effectiveness of these drugs in millions of patients depending on GLP-1 receptor agonists for the treatment of T2D and/or obesity

The increasing prevalence of DM, ASCVD, and CKD necessitates therapeutic strategies that are not only effective and safe but also accessible and scalable

Among them, liraglutide has proven to be one of the most commonly prescribed pharmacotherapy for treating obesity, due in large part to the pronounced weight loss and relatively modest profile of adverse events 21,22,53