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GLP-1 additionally exerts various effects outside the pancreas, including regulation of food intake and appetite (12), inhibition of gastrointestinal motility and secretion (13) and a cardioprotective effect (14,15)
Insulin resistance in adipose tissue, which is often related to obesity, compromises the inhibitory effects of insulin on adipose tissue lipolysis, leading to increased free fatty acids (FFAs) in portal circulation 4,5,6
Many people do better with smaller, protein-focused meals throughout the day instead of forcing themselves to eat large portions
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