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Intellectual property implications The semaglutide case highlights the ongoing debate between patent protection for innovation and broader access to medicines
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Individualized Virtual Integrative Medicine (IVIM): A Clinical Model for Enhanced GLP-1 Therapeutic Outcomes. Obesity Pillars , vol
For the primary composite outcome and secondary hierarchical outcomes, the threshold for two-sided statistical significance was set to 0.0322 (one-sided level 0.00161) using Lan-DeMets alpha spending function, which allows to adjust significance levels as data were reviewed for the interim analysis, reducing the chance of false positive results
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