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The results of the excretion experiment showed that the main excretory pathways of BPC157 involve the liver and kidney, which was also consistent with the excretion characteristics of peptide drugs (Czock et al., 2012
In such cases, residual beta-cell function is insufficient to produce meaningful glycemic improvement, and combination therapy with basal insulin or other agents becomes necessary
Repurpose of the antibiotic NFT as activator of Nrf2 could thus be a promising strategy for a transient and targeted activation of the endogenous antioxidant machinery
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