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GLP-1 receptor agonists enhance glucose-dependent insulin secretion from pancreatic beta cells, meaning they stimulate insulin release only when blood glucose levels are elevated
In fact, its probably the biggest barrier to increasing use of this medication. For physicians, another large challenge when prescribing GLP-1RA medications includes lack of clinical guidelines for offlabel prescribing
However, semaglutide can influence certain blood test results, which is an important distinction for patients and clinicians to understand
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