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Symptoms, neurological findings, anaemia, adherence, the underlying cause and response over time all matter
if you don't have one, a sturdy plastic jug with a screw-on lid (an empty laundry detergent bottle is the classic example) will do in a pinch
Starting too high is the single most common mistake, and it leads to unnecessary gastrointestinal distress that could have been avoided with proper titration
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