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Long-term trials like LEADER confirmed cardiovascular and renal safety for liraglutide in T2D, with no increased risk of pancreatitis or thyroid malignancy [34]
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Semaglutide was an ideal candidate for oral delivery with SNAC due to its low molecular weight (4,113.6 Da), long half-life (~ 7 days after subcutaneous administration), and high potency relative to other peptides [14, 40, 46, 56]
Armendariz, RN, FNP-C, AOCNP
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