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The tirzepatide SmPC also notes that oral contraceptive efficacy may be reduced during initiation and dose escalation, suggesting additional contraceptive measures may be needed

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Compound Overview Tirzepatide is a first-in-class dual incretin receptor agonist that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors

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The increased availability and effectiveness of GLP-1s at curbing appetite is adding to the vulnerabilities for some people prone to eating disorders

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