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Ask yourself whether any of these apply: You have type 2 diabetes or prediabetes You use insulin or other glucose-lowering drugs You have had past pancreatitis or kidney disease You have severe GERD You have sleep apnea or heavy snoring You have a history of alcohol use disorder You take other medicines that do not mix well with alcohol, such as: Opioids Benzodiazepines Certain antidepressants If one or more of these fit, drinking while on tirzepatide may carry more risk

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If nausea becomes a problem, let your doctor know

1A) using fluorescence-activated cell sorting (FACS) analysis of the the lipid peroxidation sensor dye BODIPY-C11