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Tirzepatide (Mounjaro, Zepbound) is a dual GIP and GLP-1 agonist that is already approved and has produced weight loss of 15 to 22% in trials
Blood pressure reactivity to stress (cold pressor test) was significantly attenuated in the combination group compared to both placebo and L-citrulline alone
A glutathione injection sidesteps that entirely, delivering the molecule into the bloodstream directly and making bioavailability a much smaller variable in the equation
Mechanistically, BPC-157 appears to favor natural homeostasis of the GABA receptor complex through pathways distinct from direct GABA-A receptor agonism
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