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This variation may be the result of differences on how various studies score caries prevalence, demographics of the population studied (such as age and gender), oral hygiene abilities, diet, and access to professional dental care

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In the GHK-Cu complex, the copper ion coordinates with multiple binding sites: the nitrogen from the histidine imidazole side chain, the alpha-amino group of glycine, the deprotonated amide nitrogen of the glycine-histidine peptide bond, and oxygen from the lysine carboxyl group, forming a square-planar pyramid configuration

Drug Testing and Analysis, 7(1), 3138