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The peptide's effects on the gastrointestinal tract involve interaction with the nitric oxide system, providing endothelium protection and angiogenic effects even in severely compromised conditions

Tirzepatide# Tirzepatide is a single 39-amino acid molecule that simultaneously activates GIP and GLP-1 receptors

Nat Rev Immunol 20(9):515516 Delgado-Roche L, Mesta F (2020) Oxidative stress as key player in severe acute respiratory syndrome coronavirus (SARS-CoV) infection