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The comparison is informative for patients considering switching medications rather than stopping entirely

Women using oral contraceptives should be aware that tirzepatide may reduce the effectiveness of these medications due to delayed gastric emptying

Alternative Option 2: Contrave (naltrexone/bupropion) Contrave is an FDA-approved prescription medication that helps change brain signaling pathways to reduce appetite and control cravings

20 It is worth emphasizing, that a recently published meta-analysis confirmed that a reduction in body mass, HbA1c level and fasting plasma glucose was more pronounced in the case of therapy with once-weekly semaglutide in comparison to once-daily liraglutide