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Both AgRP and NPY axons that co-localize GABA project onto POMC expressing cells in the ARC and the AgRP-stimulated release of GABA results in inhibition of the activity of the POMC neurons, an effect also seen with NPY

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The peptide promotes osteoblast attachment, increases collagen synthesis in bone cells, and has demonstrated enhanced outcomes in ACL reconstruction studies in rats when administered via articular injection at 0.3 mg/mL