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References Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA
If bloodwork shows IGF-1 remains elevated but you no longer feel the recovery and sleep benefits, the receptor response is downregulating despite adequate GH production
On metabolic stress, ASCT2 ( SLC1A5 ), LAT1 ( SLC7A5 ), CAT1 ( SLC7A1 ), GLYT1 ( SLC6A9 ), and xCT, the light chain subunit of system (SLC7A11), are elevated by ATF4 activation, which facilitates the uptake of glutamine, leucine, arginine, lysine, glycine, and cystine (Lopez et al., 2007
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