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Increased postprandial GLP-1 levels observed predominantly in male Tmprss2 / mice indicated an additional sex-specific mechanism unrelated to the activation of PAR2 by TMPRSS2
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She also cited concerns that medications such as tirzepatide could also reduce the effectiveness of oral contraceptives by reducing their absorption
Support was also provided by: University of Washington Cystic Fibrosis Research and Translation Center (National Institutes of Health grant P30 DK-089507), through a Pilot and Feasibility Award (to S.Z.) and work performed in the core facilities
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