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In breast cancer research, network tools such as Cytoscape (292), STRING (293), and Weighted Gene Co-expression Network Analysis (WGCNA) (294) have characterized several functional modules, such as the PD-L1/PD-1 axis, cyclin-dependent kinases (CDKs), BRCA1/2 complexes, and more, by analyzing transcriptomics and proteomics together
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However, the downstream receptor signalling cascade diverges substantially
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