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GSTs are able to conjugate glutathione (-l-glutamyl-l-cysteinyl-glycine, GSH) to a wide range of hydrophobic and electrophilic molecules including many carcinogens, therapeutic drugs, and many products of oxidative metabolism, making them less toxic and predisposed to further modification for discharge from the cell (Fig

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In addition, quercetin may reduce iron overload-induced injury through the ROS/ADMA/DDAH and II/eNOS/NO pathways ( These factors make it possible for quercetin to be effectively used in chelotherapy under conditions of iron overload