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For example, encapsulation of Liraglutide, a long-acting GLP-1, in PLGA NPs significantly protected the drug from degradation in simulated gastric and intestinal fluids
Formulation and dosing are customized
These approaches enable investigation of GSH/GSSG redox systems, glutathione-associated enzyme activity, thiol chemistry, and redox-regulated biochemical processes
As illustrated in Figure 1, this review comprehensively analyzes the mechanistic basis of GLP-1RAs in ocular diseases, synthesizes emerging clinical and preclinical evidence, and underscores their potential to redefine therapeutic strategies for vision-threatening disorders through multi-targeted disease modification
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