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Although GLP-1RAs can reduce body weight by 15%25% in controlled settings, real-world adherence is limited, and nearly 70% of patients experience weight regain after discontinuation, raising the risk of long-term pharmacological dependence ( Looking ahead, the future of GLP-1based therapy will depend on addressing safety concerns, improving long-term adherence, and expanding clinical indications
Gray KM, et al
The higher dose brings stronger side effects that you were not prepared for at 7am, leading to a miserable workday
Tirzepatide (Mounjaro), a dual GLP-1/GIP receptor agonist, received UK approval for type 2 diabetes and is under evaluation for obesity treatment
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