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Funding This work was supported by grants from the National Natural Science Foundation (81972259, 82273394), the Clinical Trials Fund from Nanjing Drum Tower Hospital and the Affiliated Hospital of Nanjing University Medical School (2024-LCYJ-PY-01), Suzhou Municipal Health Commission (SKYD2022034), and the discipline construction and support project (XKTJ-JD202006) of the Second Affiliated Hospital of Soochow University
Research duration varies by study objectives, with metabolic research often requiring extended timelines to observe meaningful outcomes
Semaglutide is a GLP-1 receptor agonist, which is a type of medication that mimics a natural hormone called glucagon-like peptide-1 (GLP-1)
Although its full physiological role remains unknown, enhancement of glucagon secretion and impairment of insulin secretion in response to GIP administration hinders the development of mono-GIP-directed therapies
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