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In patients with chronic granulomatous disease (CGD), neutrophil deficiencies impair the ability to combat specific fungal and bacterial infections, resulting in prolonged pro-inflammatory responses and consequent tissue damage
In order to explore the skin repair effect of RGD-GHK, we first used an in vitro cell scratch assay to examine the healing effects of peptides and a positive control epidermal growth factor (EGF)
However, the suitability of current in vitro models, including those based on ARPE-19 cells, for accurately recapitulating RPE physiology in the context of diabetes warrants further optimization
J Chem Soc Chem Commun
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