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Ushimaru et al., 2006

How Blue Copper Peptide Fights Skin Aging: The Science 01 Collagen Synthesis (Reconstructing Dermal Support) : Within 6 to 8 weeks of use, it regulates gene expression of Type I and Type III collagen in fibroblasts, improving firmness and reducing fine lines

In normal subjects: GHRH alone: GH secretion of 483.7 GHRP-6 alone: GH secretion of 1434.8 GHRH plus GHRP-6: GH secretion of 3771.5 The combined output is not 1918.5 (the additive sum)