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Recent head-to-head clinical trials have directly compared tirzepatide (e.g., Zepbound) to semaglutide (e.g., Wegovy) for weight loss in individuals with obesity but without diabetes
2,339 adults without diabetes, randomized to 4mg/9mg/12mg/placebo over 80 weeks
Higher visceral fat was linked to higher levels of both anxiety and depression
Why GLP-1 Medications Work Best with a Functional Medicine Approach While GLP-1 medications like semaglutide can be highly effective for weight loss, they work even better when combined with a personalized, integrative plan
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