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One unique finding was an imbalance in diabetic retinopathy complications in SUSTAIN-6: 3.0% of semaglutide patients vs 1.8% of placebo had retinopathy progression ( [133] )
The widespread popularity of the medication has caused prescription drug costs to skyrocket over the past several years, leading insurance carriers to no longer cover the medication for weight loss
These drugs activate the cAMP/PKA/CREB pathway to boost BDNF expression
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