Taken together, the upregulation of DETs across all three central detoxification mechanisms in viruliferous BLHs may have contributed to their enhanced tolerance to neonicotinoids compared to non-viruliferous BLHs
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Therefore, the use of several sub-strains of mice is a strength of this study [49, 50], and suggests that our findings are more likely to generalize to other mouse sub-strains than they would have if the study were conducted in only one strain of mice